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Potential Adverse Human Health Effects
of the Top 25 TRI Chemicals

Source: EPA 1994 Toxics Release Inventory
Public Data Release, Chapter 1


CHEMICAL ACUTE CANCER2 CHRONIC DEVELOP-
MENTAL
REPRO-
DUCTIVE
NEURO-
TOXICITY
OTHER3
Methanol X X
Ammonia X
Toluene X
Xylene (mixed isomers)
Carbon disulfide X X X X
Zinc compounds X X X
Methyl ethyl ketone
Phosphoric acid
Hydrochloric acid X4 X5
Dichloromethane X X X
Chlorine X
Glycol ethers X X X X
Copper compounds X X
Manganese compounds X X X
Styrene X X
1,1,1-Trichloroethane
Ethylene X
Trichloroethylene X
n-Butyl alcohol X
Methyl isobutyl ketone X X
Sulfuric acid (acid aerosols) X
Chromium compounds X X6 X X X
Propylene
Carbonyl sulfide X X
Lead compounds X X7 X X X X

1From Chapter 1, box 4, 1994 Toxics Release Inventory: Public Data Release, EPA-745-R-96-002. (Sources: Integrated Risk Management System, Hazardous Substances Data Bank, OPPT's Background Documents for Chemical Fact Sheets, EPCRA Section 313 Responses to Petitions, Agency for Toxic Substances and Disease Registry's Toxicological Profiles, and Environmental Health Perspective, Vol. 37, 1984.)
2Distinctions among cancer classifications are discussed in the OSHA carcinogen section of this chapter.
3Toxicity resulting from the metabolite or degradation product of the parent compound.
4Concentrated solutions are corrosive.
5Aerosol forms.
6Chromium VI is carcinogenic.
7Inorganic compounds.

Source: USEPA 1994 Toxics Release Inventory Public Data Release (EPA 745-R-96-002, June 1996).

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